教員紹介

ISHIBASHI Yohei

Profile

Outline Activities

Thraustochytrids are marine microorganisms that produce and accumulate high levels of useful lipids such as poly unsaturated fatty acids and sterols. To improve lipid productivity, or produce new useful lipids, we are trying to identify the lipid metabolizing enzymes, their regulators, and factors contributing to lipid accumulation in lipid droplet. We are also conducting basic research to elucidate the biological functions of specific lipid molecules by taking advantage of the ability of thraustochytrid that can synthesize a wide variety of lipid molecular species. In addition, we are conducting research that will lead to the development of new antifungal drugs through the functional analysis of novel glycolipid hydrolyzing enzymes unique to fungi.

Message

Lipids are useful compounds with a wide range of applications, including food, chemical products, pharmaceuticals, aquaculture feed, and biofuels. The main sources are fish, livestock products, and oilseed plant seeds. However, from the perspective of climate change, environmental protection, and avoiding competition with food resources, there is a need to establish a sustainable microbial lipid production system that does not depend on animal and plant resources. The marine microorganism, thraustochytrids can synthesize and accumulate large amounts of various useful lipids. Microscopic examination of these microorganisms reveals that lipid droplets that contribute the lipid accumulation occupy the majority of their intracellular space. We hope to utilize this microorganism's remarkable ability to produce and accumulate lipids to create an innovative lipid production system that can meet all kinds of needs, thereby contributing to sustainable society.

Educational Activities

Undergraduate School

Laboratory Exercise in Marine Resource Chemistry
Marine Microbiology I

Graduate School