Contact
Access Map
教員紹介
FURUYA Shigeki
Research Interests
“Regulation of brain metabolism and function by food proteins/peptides”
“Functional genomics analysis of nutrient-gene interaction using knockout mice lacking amino acid biosynthesis”
Profile
Outline Activities
Our laboratory is interested in understanding molecular and cellular mechanisms that regulate responses to limited availability of simple nutrients amino acids in animals. Over the last several years, we have focused in particular on the physiological role of serine biosynthesis in the development and function of brain. We have used targeted gene disruption approach to create mouse models of human serine deficiency disorder, which exhibits severe neurological symptoms in patients. Current projects being undertaken are: 1) Functional genomics analysis of knockout mice lacking serine biosynthesis. 2) Development of an integrative omics platform for analysis of mouse models of human serine deficiency disorder. 3) Characterization of the mechanisms underlying growth retarded phenotypes exhibited by mice lacking serine biosynthesis. 4) Development of in vivo bioassay system for screening food components enhancing brain function.
Message
Educational Activities
Undergraduate School
Life Chemistry,Food Science
Graduate School
Advanced in Metabolic Homeostasis Regulation