研究室紹介

Molecular Gene Technology

Regulatory networks function in the maintenance, adaptation and development of life. We focus on the transcriptional regulation mechanisms, and study the regulatory network in single-cellular and in multicellular organization. Our research topics include: the cellular gene regulation system using experimental and computational strategy, gene regulation in cellular differentiation, the development of devices for analysis of environmental microorganisms, and structural analysis of various organisms genome structure.

Research Interests

1. Elucidation of the epigenetic regulatory system of cell differentiation
2. Elucidation of the regulatory system of invasive potential of cancer cells
3. Regulatory system of cytokine action in inflammation
4. Analysis of the human ceramide synthesis system in yeast
5. Development of microbial culture system by WODL
6. Development of animal cell culture system by WODL
7. Development of a computer-based analysis method for gene expression control mechanisms
8. Genome information analysis

In the Department of Molecular Gene Regulation, our research targets a wide range of biological phenomena, from universal phenomena found in microorganisms to higher-order cellular functions in higher vertebrates, and aims to elucidate the basis of biological phenomena by focusing on the elucidation of gene regulation mechanisms. In our research, our main methodology is experimental biology, in which data is collected and analyzed using molecular and cellular biology methods, but we also organically incorporate computer science, or bioinformatics, methodologies using computers to elucidate biological phenomena. We also use omics data such as transcriptome and proteome obtained through the genome project, as well as genomic information from next-generation sequencers.

Keyword of Research Area